Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

Colocalization of MCM8 and MCM7 with proteins involved in distinct aspects of DNA replication

Yayoi Kinoshita, Edward M. Johnson, Ronald E. Gordon, Heather Negri-Bell, Mark T. Evans, Jennifer Coolbaugh, Yaseris Rosario-Peralta, Joseph Samet, Evelyn Slusser, Mark P. Birkenbach, Dianne C. Daniel

Microscopy Research and Technique DOI: 10.1002/jemt.20553
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Publication Alert

Dormant origins licensed by excess Mcm2–7 are required for human cells to survive replicative stress

Xin Quan Ge, Dean A. Jackson, and J. Julian Blow

GENES & DEVELOPMENT 21:3331-3341, 2007
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Publication Alert

The role of pre-replicative complex (pre-RC) components in oncogenesis

Eric Lau, Toshiya Tsuji, Liping Guo, Shih-Hsin Lu and Wei Jiang

The FASEB Journal. 2007;21:3786-3794
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Publication Alert

The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

Katsuhiro Hanada, Magda Budzowska, Sally L Davies, Ellen van Drunen, Hideo Onizawa, H Berna Beverloo, Alex Maas, Jeroen Essers, Ian D Hickson & Roland Kanaar

Nature Structural & Molecular Biology 14, 1096 - 1104 (2007) 

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Publication Alert

The Origin Recognition Complex Localizes to Telomere Repeats and Prevents Telomere-Circle Formation

Zhong Deng, Jayaraju Dheekollu, Dominique Broccoli, Anindya Dutta, and Paul M. Lieberman

Current Biology, Vol 17, 1989-1995, 20 November 2007
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Publication Alert

Cyclin B2 suppresses mitotic failure and DNA re-replication in human somatic cells knocked down for both cyclins B1 and B2

S Bellanger, A de Gramont,and J Sobczak-Thépot

Oncogene (2007) 26, 7175–7184
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Publication Alert

Knockdown of human MCM10 exhibits delayed and incomplete chromosome replication

Jong Hoon Park, Sung Woong Bang, Yesu Jeon, Sukhyun Kang and Deog Su Hwang

Biochemical and Biophysical Research Communications Volume 365, Issue 3, 18 January 2008, Pages 575-582
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Publication Alert

Knockdown of human MCM10 activates G2 checkpoint pathway

Jong Hoon Parka, Sung Woong Bangb, Sung Ho Kima and Deog Su Hwang

Biochemical and Biophysical Research Communications Volume 365, Issue 3, 18 January 2008, Pages 490-495
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Publication Alert

Functional differentiation and cooperative interaction between two eukaryote-like archaeal Orc1/Cdc6 proteins on the replication origin

Pei-Xia Jianga, Ying Fenga and Zheng-Guo He

Biochemical and Biophysical Research Communications Volume 364, Issue 4, 28 December 2007, Pages 945-951
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Publication Alert

Interactions and subcellular distribution of DNA replication initiation proteins in eukaryotic cells

Normen Brand, Thomas Faul and Friedrich Grummt

Molecular Genetics and Genomics 1617-4615 Volume 278, Number 6 / December, 2007
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Publication Alert

DNA Combing Reveals Intrinsic Temporal Disorder in the Replication of Yeast Chromosome VI

Daniel M. Czajkowsky, Jie Liu, Joyce L. Hamlin and Zhifeng Shao

Journal of Molecular Biology Volume 375, Issue 1, 4 January 2008, Pages 12-19
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Publication Alert

Conservation of Epigenetic Regulation, ORC Binding and Developmental Timing of DNA Replication Origins in the Genus Drosophila

B. R. Calvi, B. A. Byrnes and A. J. Kolpakas

Genetics, Vol. 177, 1291-1301
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Publication Alert

Sequential and Synergistic Modification of Human RPA Stimulates Chromosomal DNA Repair

Rachel W. Anantha, Vitaly M. Vassin, and James A. Borowiec

Vol. 282, Issue 49, 35910-35923, December 7, 2007
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Publication Alert

Dynamics of human replication factors in the elongation phase of DNA replication

Yuji Masuda1 Miki Suzuki1, Jinlian Piao, Yongqing Gu, Toshiki Tsurimoto and Kenji Kamiya

Nucleic Acids Research 2007 35(20):6904-6916; doi:10.1093/nar/gkm822
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Publication Alert

Site-specific interaction of the murine pre-replicative complex with origin DNA: assembly and disassembly during cell cycle transit and differentiation

Elisabeth Zellner, Thomas Herrmann, Carsten Schulz and Friedrich Grummt

Nucleic Acids Research 2007 35(20):6701-6713;
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