Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Deficiency in Origin Licensing Proteins Impairs Cilia Formation: Implications for the Aetiology of Meier-Gorlin Syndrome Tom Stiff, Meryem Alagoz,Diana Alcantara, Emily Outwin, Han G. Brunner, Ernie M. H. F. Bongers, Mark O'Driscoll, Penny A. Jeggo PLoS Genet 9(3): e1003360
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Cdc45 Protein-Single-stranded DNA Interaction Is Important for Stalling the Helicase during Replication Stress Irina Bruck and Daniel L. Kaplan J. Biol. Chem. 2013 288: 7550-7563.
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In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2–7 hexamer dimerization Cecile Evrin, Alejandra Fernández-Cid, Juergen Zech, M. Carmen Herrera, Alberto Riera, Pippa Clarke, Shlomo Brill, Rudi Lurz, and Christian Speck Nucl. Acids Res. 2013 41: 3162-3172
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Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology Ian M. Slaymaker, Yang Fu, Daniel B. Toso, Nimna Ranatunga, Aaron Brewster, Susan L. Forsburg, Z. Hong Zhou, and Xiaojiang S. Chen Nucl. Acids Res. 2013 41: 3446-3456
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The Fission Yeast Minichromosome Maintenance (MCM)-binding Protein (MCM-BP), Mcb1, Regulates MCM Function during Prereplicative Complex Formation in DNA Replication Venny Santosa, Sabrina Martha, Noriaki Hirose, and Katsunori Tanaka J. Biol. Chem. 2013 288: 6864-6880.
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SCFFbxw15 Mediates Histone Acetyltransferase Binding to Origin Recognition Complex (HBO1) Ubiquitin-Proteasomal Degradation to Regulate Cell Proliferation Chunbin Zou, Yan Chen, Rebecca M. Smith, Courtney Snavely, Jin Li, Tiffany, A. Coon, Bill B. Chen, Yutong Zhao, and Rama K. Mallampalli J. Biol. Chem. 2013 288: 6306-6316.
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Sequential steps in DNA replication are inhibited to ensure reduction of ploidy in meiosis Hui Hua, Mandana Namdar, Olivier Ganier, Juraj Gregan, Marcel Méchali, and Stephen E. Kearsey Mol. Biol. Cell 2013 24:5 578-587
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