Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

30-Aug-2010 14:43 | Permalink
Pre-Steady State Kinetic Studies of the Fidelity of Nucleotide Incorporation by Yeast DNA Polymerase δ

Lynne M. Dieckman, Robert E. Johnson, Satya Prakash and M. Todd Washington

Biochemistry, 2010, 49 (34), pp 7344–7350
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Publication Alert

30-Aug-2010 14:42 | Permalink
Methylated DNA Causes a Physical Block to Replication Forks Independently of Damage Signalling, O6-Methylguanine or DNA Single-Strand Breaks and Results in DNA Damage

Petra Groth, Simon Ausländer, Muntasir Mamun Majumder, Niklas Schultz, Fredrik Johansson, Eva Petermann and Thomas Helleday

Journal of Molecular Biology Volume 402, Issue 1, 10 September 2010, Pages 70-82
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Publication Alert

30-Aug-2010 14:41 | Permalink
Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization

Supriya G. Prasantha, Zhen Shen, Kannanganattu V. Prasanth, and Bruce Stillman

PNAS August 24, 2010 vol. 107 no. 34 15093-15098
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Publication Alert

30-Aug-2010 14:41 | Permalink
A chromatin-bound kinase, ERK8, protects genomic integrity by inhibiting HDM2-mediated degradation of the DNA clamp PCNA

Angela L. Groehler and Deborah A. Lannigan

JCB vol. 190 no. 4 575-586
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Publication Alert

30-Aug-2010 14:39 | Permalink
Replication Termination at Eukaryotic Chromosomes Is Mediated by Top2 and Occurs at Genomic Loci Containing Pausing Elements

Daniele Fachinetti,Rodrigo Bermejo,Andrea Cocito,Simone Minardi,Yuki Katou,Yutaka Kanoh,Katsuhiko Shirahige,Anna Azvolinsky,Virginia A. Zakian, Marco Foiani

Molecular Cell, Volume 39, Issue 4, 595-605, 27 August 2010
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Publication Alert

21-Aug-2010 06:49 | Permalink
Loss of DNA Replication Control Is a Potent Inducer of Gene Amplification

Brian M. Green, Kenneth J. Finn, and Joachim J. Li

Science 20 August 2010: 943-946.
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Publication Alert

21-Aug-2010 06:48 | Permalink
Regulation of heterochromatic DNA replication by histone H3 lysine 27 methyltransferases

Yannick Jacob, Hume Stroud, Chantal LeBlanc, Suhua Feng, Luting Zhuo, Elena Caro, Christiane Hassel, Crisanto Gutierrez, Scott D. Michaels & Steven E. Jacobsen

Nature 466, 987–991 (19 August 2010)
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Publication Alert

21-Aug-2010 06:47 | Permalink
FEN1 Ensures Telomere Stability by Facilitating Replication Fork Re-initiation

Abhishek Saharia, Daniel C. Teasley, Julien P. Duxin, Benjamin Dao, Katherine B. Chiappinelli, and Sheila A. Stewart

J. Biol. Chem. 2010 285: 27057-27066.
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Publication Alert

16-Aug-2010 16:35 | Permalink
Homologous Recombination Restarts Blocked Replication Forks at the Expense of Genome Rearrangements by Template Exchange

Sarah Lambert,Ken'ichi Mizuno,Joël Blaisonneau,Sylvain Martineau,Roland Chanet,Karine Fréon,Johanne M. Murray,Antony M. Carr,Giuseppe Baldacci

Molecular Cell, Volume 39, Issue 3, 346-359, 13 August 2010
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Publication Alert

16-Aug-2010 16:34 | Permalink
Regulation of DNA Repair through DeSUMOylation and SUMOylation of Replication Protein A Complex

Hong Dou,Chao Huang,Melissa Singh,Phillip B. Carpenter,Edward T.H. Yeh

Molecular Cell, Volume 39, Issue 3, 333-345, 13 August 2010
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Publication Alert

09-Aug-2010 10:23 | Permalink
Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase ϵ in the presence of replication protein A and proliferating-cell nuclear antigen

Giada A. Locatelli, Helmut Pospiech, Nicolas Tanguy Le Gac, Barbara van Loon, Ulrich Hubscher, Sinikka Parkkinen, Juhani E. Syväoja and Giuseppe Villani

Biochem. J. (2010) 429 (573–582)
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Publication Alert

09-Aug-2010 10:23 | Permalink
Accessibility of the Drosophila genome discriminates PcG repression, H4K16 acetylation and replication timing

Oliver Bell, Michaela Schwaiger, Edward J Oakeley, Florian Lienert, Christian Beisel, Michael B Stadler & Dirk Schübeler

Nature Structural & Molecular Biology 17, 894–900 (2010)
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09-Aug-2010 10:22 | Permalink
Geminin and Brahma act antagonistically to regulate EGFR–Ras–MAPK signaling in Drosophila

Anabel Herr, Lisa Mckenzie, Randy Suryadinata, Martin Sadowski, Linda M. Parsons, Boris Sarcevic and Helena E. Richardson

Developmental Biology Volume 344, Issue 1, 1 August 2010, Pages 36-51
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Publication Alert

09-Aug-2010 10:21 | Permalink
Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase

Sivaraja Vaithiyalingam, Eric M. Warren, Brandt F. Eichman, and Walter J. Chazin

PNAS August 3, 2010 vol. 107 no. 31 13684-13689
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09-Aug-2010 10:21 | Permalink
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling

Jun-Hyuk Choia, Laura A. Lindsey-Boltza, Michael Kempa, Aaron C. Masonb, Marc S. Woldb, and Aziz Sancara

PNAS August 3, 2010 vol. 107 no. 31 13660-13665
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09-Aug-2010 10:20 | Permalink
Identification of a Coiled Coil in Werner Syndrome Protein That Facilitates Multimerization and Promotes Exonuclease Processivity

J. Jefferson P. Perry, Aroumougame Asaithamby, Adam Barnebey, Foad Kiamanesch, David J. Chen, Seungil Han, John A. Tainer, and Steven M. Yannone

J. Biol. Chem. 2010 285: 25699-25707.
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Publication Alert

09-Aug-2010 10:19 | Permalink
The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication

Rebecca L. Ferguson, Gaetan Pascreau and James L. Maller

Journal of Cell Science 123, 2743-2749 (2010)
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Publication Alert

09-Aug-2010 10:18 | Permalink
Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA

Oren Parnas, Adi Zipin-Roitman, Boris Pfander, Batia Liefshitz, Yuval Mazor, Shay Ben-Aroya, Stefan Jentsch and Martin Kupiec

The EMBO Journal (2010), 29, 2611 - 2622;
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Publication Alert

02-Aug-2010 13:31 | Permalink
Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA

Máté Gyimesi1, Kata Sarlós1 and Mihály Kovács

Nucleic Acids Research, 2010, Vol. 38, No. 13 4404-4414

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Publication Alert

02-Aug-2010 13:30 | Permalink
DNA Damage Signaling Recruits the Rtt107-Slx4 Scaffolds via Dpb11 to Mediate Replication Stress Response p300

Patrice Y. Ohouo, Francisco M. Bastos de Oliveira, Beatriz S. Almeida, Marcus B. Smolka

Molecular Cell, Volume 39, Issue 2, 300-306
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