Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Mechanisms for initiating cellular DNA replication Franziska Bleichert, Michael R. Botchan, James M. Berger Science Vol 355, Issue 6327 24 February 2017
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The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport ELIZABETH O’BRIEN, MARILYN E. HOLT, MATTHEW K. THOMPSON, LAUREN E. SALAY, AARON C. EHLINGER, WALTER J. CHAZIN, JACQUELINE K. BARTON Science Vol 355, Issue 6327 24 February 2017
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A Positive Amplification Mechanism Involving a Kinase and Replication Initiation Factor Helps Assemble the Replication Fork Helicase Irina Bruck, Nalini Dhingra, and Daniel L. Kaplan J. Biol. Chem. 2017; 292:3062-3073
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Residues in the RecQ C-terminal Domain of the Human Werner Syndrome Helicase Are Involved in Unwinding G-quadruplex DNA Amit Ketkar, Markus Voehler, Tresor Mukiza, and Robert L. Eoff J. Biol. Chem. 2017; 292:3154-3163
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Novel roles of HP1a and Mcm10 in DNA replication, genome maintenance and photoreceptor cell differentiation Nicole Vo Dang Ngoc Anh Suong Natsuki Yoshino Hideki Yoshida Sue Cotterill Masamitsu Yamaguchi Nucleic Acids Res (2017) 45 (3): 1233-1254.
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Disentangling polydispersity in the PCNA−p15PAF complex, a disordered, transient and multivalent macromolecular assembly Tiago N. Cordeiro Po-chia Chen Alfredo De Biasio Nathalie Sibille Francisco J. Blanco Jochen S. Hub Ramon Crehuet Pau Bernadó Nucleic Acids Res (2017) 45 (3): 1501-1515.
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Repair of Meiotic DNA Breaks and Homolog Pairing in Mouse Meiosis Requires a Minichromosome Maintenance (MCM) Paralog Adrian J. McNairn, Vera D. Rinaldi, John C. Schimenti Genetics February 2017 205: 529-537
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Pif1-family helicases cooperatively suppress widespread replication-fork arrest at tRNA genes Joseph S Osmundson, Jayashree Kumar, Rani Yeung & Duncan J Smith Nature Structural & Molecular Biology 24, 162–170 (2017)
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A long noncoding RNA in DNA replication and chromosome dynamics Francesco P. Marchese & Maite Huarte Cell cycle 16 Pages 151-152
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DNA replication stress: NoCut to the rescue Nuno Amaral, Nicola Brownlow & Manuel Mendoza Cell cycle 16 Pages 233-234
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Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork Katherine N. Choe2, George-Lucian Moldovan Molecular Cell Volume 65, Issue 3, p380–392, 2 February 2017
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Recruitment of Fkh1 to replication origins requires precisely positioned Fkh1/2 binding sites and concurrent assembly of the pre- replicative complex Allan Reinapae, Kristiina Jalakas, Nikita Avvakumov, Marko Lõoke, Kersti Kristjuhan, Arnold Kristjuhan PLoS Genet 13(1): e1006588.
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Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation Roxana Georgescu, Zuanning Yuan, Lin Bai, Ruda de Lun Almeida Santos, Jingchuan Sun, Dan Zhang, Olga Yurieva, Huilin Lic and Michael E. O’Donnell PNAS 2017 114 (5) E697-E706
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