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24-Dec-2022 17:24
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Human DNA polymerase α has a strong mutagenic potential at the initial steps of DNA synthesis
Alisa E Lisova, Andrey G Baranovskiy, Lucia M Morstadt, Nigar D Babayeva, Tahir H Tahirov
Nucleic Acids Research, Volume 50, Issue 21, 28 November 2022, Pages 12266–12273,
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24-Dec-2022 17:21
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New insights into DNA polymerase mechanisms provided by time-lapse crystallography
Tyler M.Weaver, M. Todd Washington, Bret D.Freudenthal
Current Opinion in Structural Biology Volume 77, December 2022, 102465
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24-Dec-2022 17:17
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Pold4 is dispensable for mouse development, DNA replication and DNA repair
XuepingGu, Qinjin Dai, PengDu, Ning Li, Jiahui Li, Simiao Zeng, Shuyi Peng, Shengjun Tang, Lei Wang, Zhongcheng Zhou
Gene Volume 851, 30 January 2023, 147029
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24-Dec-2022 17:13
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Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation
Martin Meagher, Alexander Myasnikov, and Eric J. Enemark
Int. J. Mol. Sci. 2022, 23(23), 14678;
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24-Dec-2022 17:12
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Global landscape of replicative DNA polymerase usage in the human genome
Eri Koyanagi, Yoko Kakimoto, Tamiko Minamisawa, Fumiya Yoshifuji, Toyoaki Natsume, Atsushi Higashitani, Tomoo Ogi, Antony M. Carr, Masato T. Kanemaki & Yasukazu Daigaku
Nature Communications volume 13, Article number: 7221 (2022)
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24-Dec-2022 17:10
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The non-catalytic role of DNA polymerase epsilon in replication initiation in human cells
Sameera Vipat, Dipika Gupta, Sagun Jonchhe, Hele Anderspuk, Eli Rothenberg & Tatiana N. Moiseeva
Nature Communications volume 13, Article number: 7099 (2022)
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24-Dec-2022 17:09
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Unscheduled DNA replication in G1 causes genome instability and damage signatures indicative of replication collisions
Karl-Uwe Reusswig, Julia Bittmann, Martina Peritore, Mathilde Courtes, Benjamin Pardo, Michael Wierer, Matthias Mann & Boris Pfander
Nature Communications volume 13, Article number: 7014 (2022)
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24-Dec-2022 17:07
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Trypanosoma brucei Mitochondrial DNA Polymerase POLIB Contains a Novel Polymerase Domain Insertion That Confers Dominant Exonuclease Activity
Stephanie B. Delzell, Scott W. Nelson, Matthew P. Frost, and Michele M. Klingbeil*
Biochemistry 23, 2751–2765 November 18, 2022
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24-Dec-2022 17:02
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Mechanistic investigation of human maturation of Okazaki fragments reveals slow kinetics
Vlad-Stefan Raducanu, Muhammad Tehseen, Amani Al-Amodi, Luay I. Joudeh, Alfredo De Biasio & Samir M. Hamdan
Nature Communications volume 13, Article number: 6973 (2022)
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24-Dec-2022 17:01
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Cell division drives DNA methylation loss in late-replicating domains in primary human cells
Jamie L. Endicott, Paula A. Nolte, Hui Shen & Peter W. Laird
Nature Communications volume 13, Article number: 6659 (2022)
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24-Dec-2022 16:59
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Unexpected new insights into DNA clamp loaders
Huilin Li, Mike O'Donnell, Brian Kelch
Bioessays Volume44, Issue11 November 2022
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24-Dec-2022 16:57
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DNA replication timing: Biochemical mechanisms and biological significance
Nicholas Rhind
Bioassays Volume44, Issue11 November 2022
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24-Dec-2022 16:55
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Replicon hypothesis revisited
Hisao Masai
Biochemical and Biophysical Research Communications Volume 633, 10 December 2022, Pages 77-80
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24-Dec-2022 16:53
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Replicon-seq: seeing is believing
Cristian Polo Rivera
Tom D. Deegan
Trends in Genetics VOLUME 38, ISSUE 10, P987-988,
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24-Dec-2022 16:50
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Profilin-1 regulates DNA replication forks in a context-dependent fashion by interacting with SNF2H and BOD1L
Cuige Zhu, Mari Iwase, Ziqian Li, Faliang Wang, Annabel Quinet, Alessandro Vindigni & Jieya Shao
Nature Communications volume 13, Article number: 6531 (2022)
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24-Dec-2022 16:47
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Global early replication disrupts gene expression and chromatin conformation in a single cell cycle
Miguel M. Santos, Mark C. Johnson, Lukáš Fiedler & Philip Zegerman
Genome Biology volume 23, Article number: 217 (2022)
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24-Dec-2022 16:46
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Epigenetic control of chromosome-associated lncRNA genes essential for replication and stability
Michael B. Heskett, Athanasios E. Vouzas, Leslie G. Smith, Phillip A. Yates, Christopher Boniface, Eric E. Bouhassira, Paul T. Spellman, David M. Gilbert & Mathew J. Thayer
Nature Communications volume 13, Article number: 6301 (2022)
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24-Dec-2022 16:44
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24-Dec-2022 16:41
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Origin recognition complex harbors an intrinsic nucleosome remodeling activity
Sai Li, Michael R. Wasserman, Olga Yurieva, Lu Bai, Michael E. O’Donnell, and Shixin Liu
PNAS 119 (42) e2211568119
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24-Dec-2022 16:39
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Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes
Hana Polasek-Sedlackova, Thomas C. R. Miller, Jana Krejci, Maj-Britt Rask & Jiri Lukas
Nature Communications volume 13, Article number: 6090 (2022)
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24-Dec-2022 16:36
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DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot in Arabidopsis
Cong Wang, Jiyue Huang, Jun Zhang, Yue Yu, Gregory P. Copenhaver, Chenjiang You, and Yingxiang Wang
PNAS 119 (41) e2208441119
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24-Dec-2022 16:33
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Rpd3 regulates single-copy origins independently of the rDNA array by opposing Fkh1-mediated origin stimulation
Yiwei He, Meghan V. Petrie, Haiyang Zhang, Jared M. Peace, and Oscar M. Aparicio
PNAS 119 (40) e2212134119
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24-Dec-2022 16:31
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ASPM promotes ATR-CHK1 activation and stabilizes stalled replication forks in response to replication stress
Xingxuan Wu, Shibin Xu, Peipei Wang,Zhao-Qi Wang, Hongxiang Chen, Xingzhi Xu , and Bin Peng
PNAS 119 (40) e2203783119
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24-Dec-2022 16:28
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The consequences of differential origin licensing dynamics in distinct chromatin environments
Liu Mei, Katarzyna M Kedziora, Eun-Ah Song, Jeremy E Purvis, Jeanette Gowen Cook
Nucleic Acids Research, Volume 50, Issue 17, 23 September 2022, Pages 9601–9620,
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24-Dec-2022 15:57
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Tracking of progressing human DNA polymerase δ holoenzymes reveals distributions of DNA lesion bypass activities
Rachel L Dannenberg, Joseph A Cardina, Kara G Pytko, Mark Hedglin
Nucleic Acids Research, Volume 50, Issue 17, 23 September 2022, Pages 9893–9908,
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24-Dec-2022 15:55
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Changes in the architecture and abundance of replication intermediates delineate the chronology of DNA damage tolerance pathways at UV-stalled replication forks in human cells
Yann Benureau, Caroline Pouvelle, Pauline Dupaigne, Sonia Baconnais, Eliana Moreira Tavares, Gerard Mazón, Emmanuelle Despras, Eric Le Cam, Patricia L Kannouche
Nucleic Acids Research, Volume 50, Issue 17, 23 September 2022, Pages 9909–9929,
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24-Dec-2022 15:53
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3D chromatin connectivity underlies replication origin efficiency in mouse embryonic stem cells
Karolina Jodkowska, Vera Pancaldi, Maria Rigau, Ricardo Almeida, José M Fernández-Justel, Osvaldo Graña-Castro, Sara Rodríguez-Acebes, Miriam Rubio-Camarillo, Enrique Carrillo-de Santa Pau, David Pisano Fátima Al-Shahrour, Alfonso Valencia, María Gómez, Juan Méndez
Nucleic Acids Research, Volume 50, Issue 21, 28 November 2022, Pages 12149–12165,