Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

28-Feb-2011 11:47 | Permalink
Eukaryotic Lagging Strand DNA Replication Employs a Multi-pathway Mechanism That Protects Genome Integrity

Lata Balakrishnan and Robert A. Bambara

J. Biol. Chem. 2011 286: 6865-6870.
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Publication Alert

20-Feb-2011 12:51 | Permalink
Reduced Stability and Increased Dynamics in the Human Proliferating Cell Nuclear Antigen (PCNA) Relative to the Yeast Homolog

Alfredo De Biasio, Ricardo Sánchez, Jesús Prieto, Maider Villate, Ramón Campos-Olivas, Francisco J. Blanco

PLoS ONE 6(2): e16600
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Publication Alert

20-Feb-2011 12:50 | Permalink
CDK prevents Mcm2–7 helicase loading by inhibiting Cdt1 interaction with Orc6

Shuyan Chen and Stephen P. Bell

Genes Dev. February 15, 2011 25: 363-372
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Publication Alert

20-Feb-2011 12:50 | Permalink
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

Avvaru N Suhasini, Nina A Rawtani, Yuliang Wu, Joshua A Sommers, Sudha Sharma, Georgina Mosedale, Phillip S North, Sharon B Cantor, Ian D Hickson and Robert M Brosh Jr

The EMBO Journal (2011), 30, 692 - 705
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Publication Alert

20-Feb-2011 12:49 | Permalink
Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis

Jane E. Ladner, Miao Pan, Jerard Hurwitz, and Zvi Kelman

PNAS February 15, 2011 vol. 108 no. 7 2711-2716
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Publication Alert

14-Feb-2011 11:50 | Permalink
TopBP1 Deficiency Causes an Early Embryonic Lethality and Induces Cellular Senescence in Primary Cells

Yoon Jeon, Eun Ko, Kyung Yong Lee, Min Ji Ko, Seo Young Park, Jeeheon Kang, Chang Hwan Jeon, Ho Lee, and Deog Su Hwang

J. Biol. Chem. 2011 286: 5414-5422.
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Publication Alert

14-Feb-2011 11:49 | Permalink
Replication protein A safeguards genome integrity by controlling NER incision events

René M. Overmeer, Jill Moser, Marcel Volker, Hanneke Kool, Alan E. Tomkinson, Albert A. van Zeeland, Leon H.F. Mullenders, and Maria Fousteri

JCB vol. 192 no. 3 401-415
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Publication Alert

14-Feb-2011 11:48 | Permalink
Amplification of a plasmid bearing a mammalian replication initiation region in chromosomal and extrachromosomal contexts

Seiyu Harada, Naoki Sekiguchi, and Noriaki Shimizu

Nucl. Acids Res. 2011 39: 958-969
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Publication Alert

14-Feb-2011 11:47 | Permalink
Functional regulation of FEN1 nuclease and its link to cancer

Li Zheng, Jia Jia, L. David Finger, Zhigang Guo, Cindy Zer,and Binghui Shen

Nucl. Acids Res. 2011 39: 781-794;
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Publication Alert

07-Feb-2011 15:25 | Permalink
Replication-compromised cells require the mitotic checkpoint to prevent tetraploidization

Zilai Zhang, Sumit Arora, Yanjiao Zhou, Athena Cherry and Teresa S.-F. Wang

CHROMOSOMA Volume 120, Number 1, 73-82
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Publication Alert

07-Feb-2011 15:25 | Permalink
Regulation of DNA replication by chromatin structures: accessibility and recruitment

Makoto T. Hayashi and Hisao Masukata

CHROMOSOMA Volume 120, Number 1, 39-46,
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Publication Alert

07-Feb-2011 15:23 | Permalink
Replication timing of pseudo-NORs

Evgeny Smirnov, Dušan Cmarko, Lubomír Kováčik, Guy M. Hagen, Alexey Popov, Otakar Raška, José-Luis Prieto, Boris Ryabchenko, Filipa Amim, Brian McStay and Ivan Rašk

Journal of Structural Biology Volume 173, Issue 2, February 2011, Pages 213-218
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Publication Alert

07-Feb-2011 15:23 | Permalink
Lysine Residue 185 of Rad1 Is a Topological but Not a Functional Counterpart of Lysine Residue 164 of PCNA

Niek Wit, Peter H. L. Krijger, Paul C. M. van den Berk, Heinz Jacobs

PLoS ONE 6(1): e16669.
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Publication Alert

07-Feb-2011 15:22 | Permalink
Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

Anne Letessier, Gaël A. Millot, Stéphane Koundrioukoff, Anne-Marie Lachagès, Nicolas Vogt, R. Scott Hansen, Bernard Malfoy, Olivier Brison & Michelle Debatisse

Nature 470, 120–123 (03 February 2011)
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Publication Alert

07-Feb-2011 15:21 | Permalink
MCM3AP Is Transcribed from a Promoter within an Intron of the Overlapping Gene for GANP

Vihandha O. Wickramasinghe, Paul I.A. McMurtrie, Jackie Marr, Yoko Amagase, Sarah Main, Anthony D. Mills, Ronald A. Laskey and Yoshinori Takei

Journal of Molecular Biology Volume 406, Issue 3, 25 February 2011, Pages 355-361
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Publication Alert

07-Feb-2011 15:20 | Permalink
Replication infidelity via a mismatch with Watson–Crick geometry

Katarzyna Bebenek, Lars C. Pedersen, and Thomas A. Kunkel

PNAS February 1, 2011 vol. 108 no. 5 1862-1867
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Publication Alert

07-Feb-2011 15:19 | Permalink
Architecture of the DNA polymerase B-proliferating cell nuclear antigen (PCNA)-DNA ternary complex

Kouta Mayanagi, Shinichi Kiyonari, Hirokazu Nishida, Mihoko Saito, Daisuke Kohda, Yoshizumi Ishino, Tsuyoshi Shiraid, and Kosuke Morikawae

PNAS February 1, 2011 vol. 108 no. 5 1845-1849
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