Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Impact of the interplay between stemness features, p53 and pol iota on replication pathway choices Michaela Ihle, Stephanie Biber, Insa S Schroeder, Christine Blattner, Miriam Deniz, Giovanna Damia, Vanesa Gottifredi, Lisa Wiesmüller Nucleic Acids Research, Volume 49, Issue 13, 21 July 2021, Pages 7457–7475,
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The emerging determinants of replication fork stability Tanay Thakar, George-Lucian Moldovan Nucleic Acids Research, Volume 49, Issue 13, 21 July 2021, Pages 7224–7238,
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DNA molecular combing-based replication fork directionality profiling Marion Blin, Laurent Lacroix, Nataliya Petryk, Yan Jaszczyszyn, Chun-Long Chen, Olivier Hyrien and Benoˆıt Le Tallec Nucleic Acids Research, 2021, Vol. 49, No. 12 e69
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Transcription shapes DNA replication initiation to preserve genome integrity Yang Liu, Chen Ai, Tingting Gan, Jinchun Wu, Yongpeng Jiang, Xuhao Liu, Rusen Lu, Ning Gao, Qing Li, Xiong Ji & Jiazhi Hu Genome Biology volume 22, Article number: 176 (2021)
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Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse Grazia Pellicanò, Mohammed Al Mamun, Dolores Jurado-Santiago, Sara Villa-Hernández, Xingyu Yin, Michele Giannattasio, Michael C. Lanz, Marcus B. Smolka, Joseph Yeeles, Katsuhiko Shirahige, Miguel García-Díaz, Rodrigo Bermejo MOL CELL ARTICLE| VOLUME 81, ISSUE 13, P2778-2792.E4, JULY 01, 2021
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Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication Helena Santos-Rosa, Gonzalo Millán-Zambrano, Namshik Han, Tommaso Leonardi, Marie Klimontova, Simona Nasiscionyte, Luca Pandolfini, Kostantinos Tzelepis, Till Bartke, Tony Kouzarides MOL CELL VOLUME 81, ISSUE 13, P2793-2807.E8, JULY 01, 2021
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Dynamics of replication origin over-activation Haiqing Fu, Christophe E. Redon, Bhushan L. Thakur, Koichi Utani, Robin Sebastian, Sang-Min Jang, Jacob M. Gross, Sara Mosavarpour, Anna B. Marks, Sophie Z. Zhuang, Sarah B. Lazar, Mishal Rao, Shira T. Mencer, Adrian M. Baris, Lorinc S. Pongor & Mirit I. Aladjem Nature Communications volume 12, Article number: 3448 (2021)
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The intra-S phase checkpoint directly regulates replication elongation to preserve the integrity of stalled replisomes Yang Liu, Lu Wang, Xin Xu, Yue Yuan, Bo Zhang, Zeyang Li, Yuchen Xie, Rui Yan, Zeqi Zheng, Jianguo Ji, Johanne M. Murray, Antony M. Carr, and Daochun Kong PNAS June 15, 2021 118 (24) e2019183118;
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Regulation of DNA duplication by the mTOR signaling pathway Zhengfu He, Peter J. Houghton, Terence M. Williams & Changxian Shen Cell cycle 20 Issue 8 Pages 742-751
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The intrinsically disordered N-terminal region of mouse DNA polymerase alpha mediates its interaction with POT1a/b at telomeres Takeshi Mizuno, Kei Hirabayashi, Sae Miyazawa, Yurika Kobayashi, Kenta Shoji, Masakazu Kobayashi, Fumio Hanaoka, Naoko Imamoto, Hidetaka Torigoe Genes to cells Volume26, Issue6 June 2021 Pages 360-380
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Unchecked nick ligation can promote localized genome re-replication Erik Johansson and John F.X. Diffley VOLUME 31, ISSUE 11, PR710-R711, JUNE 07, 2021
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The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe–S cluster in DNA polymerase δ Denis A Kiktev, Margaret Dominska, Tony Zhang, Joseph Dahl, Elena I Stepchenkova, Piotr Mieczkowski, Peter M Burgers, Scott Lujan, Adam Burkholder, Thomas A Kunkel and Thomas D Petes Nucleic Acids Research, Volume 49, Issue 10, 4 June 2021, Pages 5623–5636,
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Budding yeast Rap1, but not telomeric DNA, is inhibitory for multiple stages of DNA replication in vitro Max E Douglas, John F X Diffley Nucleic Acids Research, Volume 49, Issue 10, 4 June 2021, Pages 5671–5683,
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Rtt105 promotes high-fidelity DNA replication and repair by regulating the single-stranded DNA-binding factor RPA Xuejie Wang, Yang Dong, Xiaocong Zhao,Jinbao Li, Jordan Lee, Zhenxin Yan, Shuangshuang Yang, Wenqiang Wu, Ximiao Hou, Guangxue Liu, Yueyue Zhang, Lun Song, Gang Cai, Qing Li, Grzegorz Ira, Xinghua Zhang, and Xuefeng Chen PNAS June 22, 2021 118 (25) e2106393118;
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Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA Premlata Kumari, Rajivgandhi Sundaram, Kodavati Manohar, Dileep Vasudevan, Narottam Acharya JBC ARTICLES IN PRESS, 100911
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