Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites Alexy Promonet, Ismaël Padioleau, Yaqun Liu, Lionel Sanz, Anna Biernacka, Anne-Lyne Schmitz, Magdalena Skrzypczak, Amélie Sarrazin, Clément Mettling, Maga Rowicka, Krzysztof Ginalski, Frédéric Chedin, Chun-Long Chen, Yea-Lih Lin & Philippe Pasero Nature Communications volume 11, Article number: 3940 (2020) https://www.nature.com/articles/s41467-020-17858-2?utm_source=ncomms_etoc&utm_medium=email&utm_campaign=toc_41467_11_1&utm_content=20200812&WT.ec_id=NCOMMS-20200812&sap-outbound-id=56E910EFFBEC9EB2C12007131304B60C4CA541E5
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Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6 Zuanning Yuan, Sarah Schneider, Thomas Dodd, Alberto Riera, Lin Bai, Chunli Yan, Indiana Magdalou,Ivaylo Ivanov, Bruce Stillman, Huilin Li, and Christian Speck PNAS July 28, 2020 117 (30) 17747-17756 https://www.pnas.org/content/117/30/17747.short?rss=1%20https://www.nature.com/articles/s41467-020-17449-1?utm_source=ncomms_etoc&utm_medium=email&utm_campaign=toc_41467_11_1&utm_content=20200812&WT.ec_id=NCOMMS-20200812&sap-outbound-id=56E910EFFBEC9EB2C12007131304B60C4CA541E5
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Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution Andrea Björkman, Søren L. Johansen, Lin Lin, Mike Schertzer, Dimitris C. Kanellis, Anna-Maria Katsori, Søren T. Christensen, Yonglun Luo, Jens S. Andersen, Simon J. Elsässer, Arturo Londono-Vallejo, Jiri Bartek and Kenneth B. Schou Genes & Dev. 2020. 34: 1065-1074 http://genesdev.cshlp.org/content/34/15-16/1065.short?rss=1
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Sir2 takes affirmative action to ensure equal opportunity in replication origin licensing Armelle Lengronne and View ORCID ProfilePhilippe Pasero PNAS July 21, 2020 117 (29) 16723-16725 https://www.pnas.org/content/117/29/16723.short?rss=1
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Active Replication Checkpoint Drives Genome Instability in Fission Yeast mcm4 Mutant Seong Min Kim, Susan L. Forsburg Mol Cell Biol 40:e00033-20. https://mcb.asm.org/content/40/14/e00033-20
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RIF1 controls replication initiation and homologous recombination repair in a radiation dose-dependent manner Yuichiro Saito, Junya Kobayashi, Masato T. Kanemaki, Kenshi Komatsu Journal of Cell Science 2020 133 https://jcs.biologists.org/content/133/12/jcs240036?rss=1
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Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome Zuanning Yuan, Roxana Georgescu, Grant D. Schauer, Michael E. O’Donnell & Huilin Li NATURE COMMUNICATIONS | (2020)11:3156 https://www.nature.com/articles/s41467-020-16910-5.pdf
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