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28-Sep-2020 09:14
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A predictable conserved DNA base composition signature defines human core DNA replication origins
Ildem Akerman, Bahar Kasaai, Alina Bazarova, Pau Biak Sang, Isabelle Peiffer, Marie Artufel, Romain Derelle, Gabrielle Smith, Marta Rodriguez-Martinez, Manuela Romano, Sandrina Kinet, Peter Tino, Charles Theillet, Naomi Taylor, Benoit Ballester & Marcel Méchali
Nature Communications volume 11, Article number: 4826 (2020)
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21-Sep-2020 09:27
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Mismatch repair and DNA polymerase δ proofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ϵ variant
Chelsea R Bulock, Xuanxuan Xing, Polina V Shcherbakova
Nucleic Acids Research, Volume 48, Issue 16, 18 September 2020, Pages 9124–9134
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21-Sep-2020 09:25
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Timeless couples G‐quadruplex detection with processing by DDX11 helicase during DNA replication
Leticia K Lerner, Sandro Holzer, Mairi L Kilkenny, Saša Šviković, Pierre Mura, Davide Schiavone, Cara B Eldridge, Alice Bittleston, Joseph D Maman, Dana Branzei, Katherine Stott, Luca Pellegrini, Julian E Sale
EMBO J (2020)39:e104185
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21-Sep-2020 09:23
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A Timeless Tale: G4 structure recognition by the fork protection complex triggers unwinding by DDX11 helicase
Catherine H Freudenreich
EMBO J (2020)39:e106305
publication alert
21-Sep-2020 09:21
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Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability
Lisa Prendergast, Urszula L. McClurg, Rossitsa Hristova, Rolando Berlinguer-Palmini, Sarah Greener, Katie Veitch, Inmaculada Hernandez, Philippe Pasero, Daniel Rico, Jonathan M. G. Higgins, Anastas Gospodinov & Manolis Papamichos-Chronakis
Nature Communications volume 11, Article number: 4534 (2020)
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07-Sep-2020 14:14
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DNA polymerase stalling at structured DNA constrains the expansion of short tandem repeats
Pierre Murat, Guillaume Guilbaud & Julian E. Sale
Genome Biology volume 21, Article number: 209 (2020)
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02124-x
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07-Sep-2020 14:13
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Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6
Jan Marten Schmidt & Franziska Bleichert
Nature Communications volume 11, Article number: 4263 (2020)
https://www.nature.com/articles/s41467-020-18067-7?utm_source=ncomms_etoc&utm_medium=email&utm_campaign=toc_41467_11_1&utm_content=20200826&WT.ec_id=NCOMMS-20200826&sap-outbound-id=0A5724557941A34A18F6B5D7E75E5E98C35DC010
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07-Sep-2020 14:12
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A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation
Estrella Guarino Almeida, Xavier Renaudin, Ashok R Venkitaraman
Nucleic Acids Research, Volume 48, Issue 14, 20 August 2020, Pages 7844–7855,
https://academic.oup.com/nar/article/48/14/7844/5870336
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07-Sep-2020 14:11
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Ctf18-RFC and DNA Pol ϵ form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication
Katy Stokes, Alicja Winczura, Boyuan Song, Giacomo De Piccoli, Daniel B Grabarczyk
Nucleic Acids Research, Volume 48, Issue 14, 20 August 2020, Pages 8128–8145
https://academic.oup.com/nar/article/48/14/8128/5862685