Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites Shyam Twayana, Albino Bacolla, Angelica Barreto-Galvez, Ruth B. De-Paula, William C. Drosopoulos, Settapong T. Kosiyatrakul, Eric E. Bouhassira, John A. Tainer, Advaitha Madireddy, and Carl L. Schildkraut PNAS November 30, 2021 118 (48) e2106477118;
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The genetic architecture of DNA replication timing in human pluripotent stem cells Qiliang Ding, Matthew M. Edwards, Ning Wang, Xiang Zhu, Alexa N. Bracci, Michelle L. Hulke, Ya Hu, Yao Tong, Joyce Hsiao, Christine J. Charvet, Sulagna Ghosh, Robert E. Handsaker, Kevin Eggan, Florian T. Merkle, Jeannine Gerhardt, Dieter Egli, Andrew G. Clark & Amnon Koren Nature Communications volume 12, Article number: 6746 (2021)
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Molecular Mechanisms of the RECQ4 Pathogenic Mutations Xiaohua Xu, Chou-Wei Chang, Min Li, Chao Liu and Yilun Liu Front. Mol. Biosci., 18 November 2021
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Replication timing analysis in polyploid cells reveals Rif1 uses multiple mechanisms to promote underreplication in Drosophila Souradip Das, Madison Caballero, Tatyana Kolesnikova, Igor Zhimulev, Amnon Koren, Jared Nordman Genetics, Volume 219, Issue 3, November 2021, iyab147,
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Error-prone, stress-induced 3′ flap–based Okazaki fragment maturation supports cell survival HAITAO SUN, ZHAONING LU, AMANPREET SINGH, YAJING ZHOU, ERIC ZHENG, MIAN ZHOU, JINHUI WANG, XIWEI WU, ZUNSONG HU, ZHAOHUI GU, JUDITH L. CAMPBELL, LI ZHENG, AND BINGHUI SHEN SCIENCE 2 Dec 2021,Vol 374, Issue 6572 pp. 1252-1258
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Chromatin loading of MCM hexamers is associated with di-/tri-methylation of histone H4K20 toward S phase entry Yoko Hayashi-Takanaka, Yuichiro Hayashi, Yasuhiro Hirano, Atsuko Miyawaki-Kuwakado, Yasuyuki Ohkawa, Chikashi Obuse, Hiroshi Kimura, Tokuko Haraguchi, Yasushi Hiraoka Nucleic Acids Research, Volume 49, Issue 21, 2 December 2021, Pages 12152–12166
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The human telomeric proteome during telomere replication Chih-Yi Gabriela Lin, Anna Christina Näger, Thomas Lunardi, Aleksandra Vančevska, Gérald Lossaint, Joachim Lingner Nucleic Acids Research, Volume 49, Issue 21, 2 December 2021, Pages 12119–12135
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Structure of a human replisome shows the organisation and interactions of a DNA replication machine Morgan L Jones, Yasemin Baris, Martin R G Taylor, Joseph T P Yeeles EMBO J (2021)40:e108819
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