Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival Aarti Yadav, Varshni Sharma , Jyoti Pal , Pallavi Gulati, Manisha Goel, Udita Chandra, Neha Bansal, Swati Saha PLoS Pathog 16(5): e1008190.
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Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA Clément Madru, Ghislaine Henneke, Pierre Raia, Inès Hugonneau-Beaufet, Gérard Pehau-Arnaudet, Patrick England, Erik Lindahl, Marc Delarue, Marta Carroni & Ludovic Sauguet Nature Communications volume 11, Article number: 1591 (2020)
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Replication Fork Barriers and Topological Barriers: Progression of DNA Replication Relies on DNA Topology Ahead of Forks Jorge B. Schvartzman Pablo Hernández Dora B. Krimer Bioessays Volume 42, Issue5 May 2020 1900204
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Determinants of Replication-Fork Pausing at tRNA Genes in Saccharomyces cerevisiae Rani Yeung and Duncan J. Smith GENETICS April 1, 2020 vol. 214 no. 4 825-838
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Rif1 Functions in a Tissue-Specific Manner To Control Replication Timing Through Its PP1-Binding Motif Robin L. Armstrong, Souradip Das, Christina A. Hill, Robert J. Duronio and Jared T. Nordman GENETICS May 1, 2020 vol. 215 no. 1 75-87
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How yeast cells deal with stalled replication forks Matan Arbel, Batia Liefshitz & Martin Kupiec Current Genetics
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Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication Romain Forey,Ana Poveda,Sushma Sharma,Antoine Barthe,Ismael Padioleau,Claire Renard,Robin Lambert,Magdalena Skrzypczak,Krzysztof Ginalski,Armelle Lengronne,Andrei Chabes,Benjamin Pardo,Philippe Pasero Mol Cell VOLUME 78, ISSUE 3, P396-410.E4,
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Separable, Ctf4-mediated recruitment of DNA Polymerase α for initiation of DNA synthesis at replication origins and lagging-strand priming during replication elongation Sarina Y. Porcella, Natasha C. Koussa, Colin P. Tang, Daphne N. Kramer, Priyanka Srivastava, Duncan J. Smith PLoS Genet 16(5): e1008755
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RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome Wei Wu, Rahul Bhowmick, Ivan Vogel, Özgün Özer, Fiorella Ghisays, Roshan S. Thakur, Esther Sanchez de Leon, Philipp H. Richter, Liqun Ren, John H. Petrini, Ian D. Hickson & Ying Liu Nature Structural & Molecular Biology volume 27, pages424–437(2020)
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SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations A. Takedachi, E. Despras, S. Scaglione, R. Guérois, J. H. Guervilly, M. Blin, S. Audebert, L. Camoin, Z. Hasanova, M. Schertzer, A. Guille, D. Churikov, I. Callebaut, V. Naim, M. Chaffanet, J. P. Borg, F. Bertucci, P. Revy, D. Birnbaum, A. Londoño-Vallejo, P. L. Kannouche & P. H. L. Gaillard Nature Structural & Molecular Biology volume 27, pages438–449(2020)
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Reconstitution of translesion synthesis reveals a mechanism of eukaryotic DNA replication restart Thomas A. Guilliam & Joseph T. P. Yeeles Nature Structural & Molecular Biology volume 27, pages450–460(2020)
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Rad53 limits CMG helicase uncoupling from DNA synthesis at replication forks Sujan Devbhandari & Dirk Remus Nature Structural & Molecular Biology volume 27, pages461–471(2020)
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Budding yeast complete DNA synthesis after chromosome segregation begins Tsvetomira Ivanova, Michael Maier, Alsu Missarova, Céline Ziegler-Birling, Monica Dam, Mercè Gomar-Alba, Lucas B. Carey & Manuel Mendoza Nature Communications volume 11, Article number: 2267 (2020)
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