Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Clamping Pol ε to the leading strand

31-Dec-2024 18:34 | Permalink
Noopur Singh & Erik Johansson Nature Structural & Molecular Biology volume 31, pages 1644–1645 (2024)
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In vivo DNA replication dynamics unveil aging-dependent replication stress

31-Dec-2024 18:33 | Permalink
Giacomo G. Rossetti, Noe ̈ lle Dommann, Angeliki Karamichali, Vasilis S. Dionellis, Ainhoa Asensio Aldave, Tural Yarahmadov, Eddie Rodriguez-Carballo, Adrian Keogh, Daniel Candinas, Deborah Stroka and Thanos D. Halazonetis Cell 187,6220–6234 2024
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Four decades of Eukaryotic DNA replication: From yeast genetics to high-resolution cryo-EM structures of the replisome

31-Dec-2024 18:31 | Permalink
Bik-Kwoon Tye PNAS 121 (42) e2415231121 2024
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Assembly and activation of replicative helicases at origin DNA for replication initiation

31-Dec-2024 18:30 | Permalink
Qiongdan Zhang, Wai Hei Lam, Yuanliang Zhai Current Opinion in Structural BiologyVolume 88 102876 2024
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A common mechanism for recruiting the Rrm3 and RTEL1 accessory helicases to the eukaryotic replisome

31-Dec-2024 18:28 | Permalink
Ottavia Olson, Simone Pelliciari, Emma D Heron, and Tom D Deegan EMBO J 43: 3846 - 3875 (2024)
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Replication licensing regulated by a short linear motif within an intrinsically disordered region of origin recognition complex

31-Dec-2024 18:27 | Permalink
Yue Wu, Qiongdan Zhang, Yuhan Lin, Wai Hei Lam & Yuanliang Zhai Nature Communications volume 15, Article number: 8039 (2024)
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USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication

31-Dec-2024 18:24 | Permalink
Hannah L. Mackay, Helen R. Stone, George E. Ronson, Katherine Ellis, Alexander Lanz, Yara Aghabi, Alexandra K. Walker, Katarzyna Starowicz, Alexander J. Garvin, Patrick Van Eijk, Stefan A. Koestler, Elizabeth J. Anthony, Ann Liza Piberger, Anoop S. Chauhan, Poppy Conway-Thomas, Alina Vaitsiankova, Sobana Vijayendran, James F. Beesley, Eva Petermann, Eric J. Brown, Ruth M. Densham, Simon H. Reed, Felix Dobbs, Marco Saponaro & Joanna R. Morris Nature Communications volume 15, Article number: 8102 (2024)
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Timely lagging strand maturation relies on Ubp10 deubiquitylase-mediated PCNA dissociation from replicating chromatin

31-Dec-2024 18:24 | Permalink
Javier Zamarreño, Sofía Muñoz, Esmeralda Alonso-Rodríguez, Macarena Alcalá, Sergio Rodríguez, Rodrigo Bermejo, María P. Sacristán & Avelino Bueno Nature Communications volume 15, Article number: 8183 (2024)
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Structures of the human leading strand Polε–PCNA holoenzyme

31-Dec-2024 18:23 | Permalink
Qing He, Feng Wang, Nina Y. Yao, Michael E. O’Donnell & Huilin Li Nature Communications volume 15, Article number: 7847 (2024)
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Pioneer factors for DNA replication initiation in metazoans

31-Dec-2024 18:22 | Permalink
Yue Wang, Jing Liang Volume46,2400002 2024
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