Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Mismatch repair and DNA polymerase δ proofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ϵ variant Chelsea R Bulock, Xuanxuan Xing, Polina V Shcherbakova Nucleic Acids Research, Volume 48, Issue 16, 18 September 2020, Pages 9124–9134
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Timeless couples G‐quadruplex detection with processing by DDX11 helicase during DNA replication Leticia K Lerner, Sandro Holzer, Mairi L Kilkenny, Saša Šviković, Pierre Mura, Davide Schiavone, Cara B Eldridge, Alice Bittleston, Joseph D Maman, Dana Branzei, Katherine Stott, Luca Pellegrini, Julian E Sale EMBO J (2020)39:e104185
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A Timeless Tale: G4 structure recognition by the fork protection complex triggers unwinding by DDX11 helicase Catherine H Freudenreich EMBO J (2020)39:e106305
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Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability Lisa Prendergast, Urszula L. McClurg, Rossitsa Hristova, Rolando Berlinguer-Palmini, Sarah Greener, Katie Veitch, Inmaculada Hernandez, Philippe Pasero, Daniel Rico, Jonathan M. G. Higgins, Anastas Gospodinov & Manolis Papamichos-Chronakis Nature Communications volume 11, Article number: 4534 (2020)
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DNA polymerase stalling at structured DNA constrains the expansion of short tandem repeats Pierre Murat, Guillaume Guilbaud & Julian E. Sale Genome Biology volume 21, Article number: 209 (2020) https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02124-x
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Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6 Jan Marten Schmidt & Franziska Bleichert Nature Communications volume 11, Article number: 4263 (2020) https://www.nature.com/articles/s41467-020-18067-7?utm_source=ncomms_etoc&utm_medium=email&utm_campaign=toc_41467_11_1&utm_content=20200826&WT.ec_id=NCOMMS-20200826&sap-outbound-id=0A5724557941A34A18F6B5D7E75E5E98C35DC010
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A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation Estrella Guarino Almeida, Xavier Renaudin, Ashok R Venkitaraman Nucleic Acids Research, Volume 48, Issue 14, 20 August 2020, Pages 7844–7855, https://academic.oup.com/nar/article/48/14/7844/5870336
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Ctf18-RFC and DNA Pol ϵ form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication Katy Stokes, Alicja Winczura, Boyuan Song, Giacomo De Piccoli, Daniel B Grabarczyk Nucleic Acids Research, Volume 48, Issue 14, 20 August 2020, Pages 8128–8145 https://academic.oup.com/nar/article/48/14/8128/5862685
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