Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Fast and efficient DNA replication with purified human proteins Yasemin Baris, Martin R. G. Taylor, Valentina Aria & Joseph T. P. Yeeles Nature 18 May 2022
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MCM complexes are barriers that restrict cohesin-mediated loop extrusion Bart J. H. Dequeker, Matthias J. Scherr, Hugo B. Brandão, Johanna Gassler, Sean Powell, Imre Gaspar, Ilya M. Flyamer, Aleksandar Lalic, Wen Tang, Roman Stocsits, Iain F. Davidson, Jan-Michael Peters, Karl E. Duderstadt, Leonid A. Mirny & Kikuë Tachibana Nature (2022) 18/5
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Kronos scRT: a uniform framework for single-cell replication timing analysis Stefano Gnan, Joseph M. Josephides, Xia Wu, Manuela Spagnuolo, Dalila Saulebekova, Mylène Bohec, Marie Dumont, Laura G. Baudrin, Daniele Fachinetti, Sylvain Baulande & Chun-Long Chen Nature Communications volume 13, Article number: 2329 (2022)
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High-throughput analysis of single human cells reveals the complex nature of DNA replication timing control Dashiell J. Massey & Amnon Koren Nature Communications volume 13, Article number: 2402
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CDC7-independent G1/S transition revealed by targeted protein degradation Jan M. Suski, Nalin Ratnayeke, Marcin Braun, Tian Zhang, Vladislav Strmiska, Wojciech Michowski, Geylani Can, Antoine Simoneau, Konrad Snioch, Mikolaj Cup, Caitlin M. Sullivan, Xiaoji Wu, Joanna Nowacka, Timothy B. Branigan, Lindsey R. Pack, James A. DeCaprio, Yan Geng, Lee Zou, Steven P. Gygi, Johannes C. Walter, Tobias Meyer & Piotr Sicinski Nature volume 605, pages 357–365 (2022)
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Molecular basis for the initiation of DNA primer synthesis Arthur W. H. Li, Katerina Zabrady, Lewis J. Bainbridge, Matej Zabrady, Sehr Naseem-Khan, Madison B. Berger, Peter Kolesar, G. Andrés Cisneros & Aidan J. Doherty Nature (2022)04 May 2022
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DNA replication fork speed underlies cell fate changes and promotes reprogramming Tsunetoshi Nakatani, Jiangwei Lin, Fei Ji, Andreas Ettinger, Julien Pontabry, Mikiko Tokoro, Luis Altamirano-Pacheco, Jonathan Fiorentino, Elmir Mahammadov, Yu Hatano, Capucine Van Rechem, Damayanti Chakraborty, Elias R. Ruiz-Morales, Paola Y. Arguello Pascualli, Antonio Scialdone, Kazuo Yamagata, Johnathan R. Whetstine, Ruslan I. Sadreyev & Maria-Elena Torres-Padilla Nature Genetics volume 54, pages 318–327 (2022)
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Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase Jiaxuan Cheng, Ningning Li, Yunjing Huo, Shangyu Dang, Bik-Kwoon Tye, Ning Gao & Yuanliang Zhai Nature Communications volume 13, Article number: 1396 (2022)
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Family D DNA polymerase interacts with GINS to promote CMG-helicase in the archaeal replisome Keisuke Oki, Mariko Nagata, Takeshi Yamagami, Tomoyuki Numata, Sonoko Ishino, Takuji Oyama, Yoshizumi Ishino Nucleic Acids Research, Volume 50, Issue 7, 22 April 2022, Pages 3601–3615,
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Single-molecule mapping of replisome progression Clémence Claussin, Jacob Vazquez, Iestyn Whitehouse Mol cell Published:March 02, 2022
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Mapping replication forks, one replicon at a time Nicholas Rhind Mol Cell VOLUME 82, ISSUE 7, P1246-1248, APRIL 07, 2022
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Stable G-quadruplex DNA structures promote replication-dependent genome instability S. Dean Rider Jr.,Rujuta Yashodhan Gadgi, David C. Hitch, Resha Shrestha, Kazuo Shin-ya, Michael Leffak JBC in press
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