Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

The GINS Complex from Pyrococcus furiosus Stimulates the MCM Helicase Activity*

Takehiro Yoshimochi, Ryosuke Fujikane, Miyuki Kawanami, Fujihiko Matsunaga, and Yoshizumi Ishino

J. Biol. Chem., Vol. 283, Issue 3, 1601-1609, January 18, 2008
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Publication Alert

A homologous recombination defect affects replication-fork progression in mammalian cells

Fayza Daboussi, Sylvain Courbet, Simone Benhamou, Patricia Kannouche, Malgorzata Z. Zdzienicka, Michelle Debatisse and Bernard S. Lopez

Journal of Cell Science 121, 162-166 (2008)
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Publication Alert

Structure of a Sliding Clamp on DNA

Roxana E. Georgescu, Seung-Sup Kim, Olga Yurieva, John Kuriyan, Xiang-Peng Kong, and Mike O'Donnell

Cell, Vol 132, 43-54, 11 January 2008
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Publication Alert

Template Switching: From Replication Fork Repair to Genome Rearrangements

Dana Branzei and Marco Foiani

Cell 131, December 28, 2007 1227 – 1230
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Publication Alert

A DNA Replication Mechanism for Generating Nonrecurrent Rearrangements Associated with Genomic Disorders

Jennifer A. Lee, Claudia M.B. Carvalho, and James R. Lupski

Cell 131, 1235–1247, December 28, 2007
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Publication Alert

Remodeling of the Human Papillomavirus Type 11 Replication Origin into Discrete Nucleoprotein Particles and Looped Structures by the E2 Protein

Jeonggu Sim, Sezgin Ozgur, Biing Yuan Lin, Jei-Hwa Yu2, Thomas R. Broker, Louise T. Chow and Jack Griffith

Journal of Molecular Biology Volume 375, Issue 4, 25 January 2008, Pages 1165-1177
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Publication Alert

Regulation of Rtt107 Recruitment to Stalled DNA Replication Forks by the Cullin Rtt101 and the Rtt109 Acetyltransferase

Tania M. Roberts, Iram Waris Zaidi, Jessica A. Vaisica, Matthias Peter, and Grant W. Brown

mol biol cell Vol. 19, Issue 1, 171-180, January 2008
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Publication Alert

Ciz1, a p21Cip1/ Waf1-interacting zinc finger protein and DNA replication factor, is a novel molecular partner for human enhancer of rudimentary homolog

Anna Łukasik, Katarzyna A. Uniewicz, Marta Kulis and Piotr Kozlowski

FEBS Journal 275 (2008) 332–340
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Publication Alert

Hbo1 Links p53-Dependent Stress Signaling to DNA Replication Licensing

Masayoshi Iizuka, Olga F. Sarmento, Takao Sekiya, Heidi Scrable, C. David Allis, and M. Mitchell Smith

Molecular and Cellular Biology, January 2008, p. 140-153, Vol. 28, No. 1
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Publication Alert

DNA-activated protein kinase functions in a newly observed S phase checkpoint that links histone mRNA abundance with DNA replication

Berndt Müller, Jane Blackburn, Carmen Feijoo, Xiujie Zhao, and Carl Smythe

The Journal of Cell Biology, Vol. 179, No. 7, 1385-1398
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Publication Alert

A conserved mechanism for replication origin recognition
and binding in archaea


Alan I. MAJERN´IK and James P. J. CHONG

Biochem. J. (2008) 409, 511–518
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Publication Alert

Characterization of the interaction between the human DNA topoisomerase IIβ -binding protein 1 (TopBP1) and the cell division cycle 45 (Cdc45) protein

Uta SCHMIDT, Yvonne WOLLMANN , Claudia FRANKE, Frank GROSSE, Hans-Peter SALUZ and Frank H ANEL

Biochem. J. (2008) 409, 169–177
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Publication Alert

Regulation of Replication Fork Progression Through Histone Supply and Demand

Anja Groth, Armelle Corpet, Adam J. L. Cook, Daniele Roche, Jiri Bartek, Jiri Lukas, Geneviève Almouzni

Science 21 December 2007:
Vol. 318. no. 5858, pp. 1928 – 1931
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Publication Alert

The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

Hanada K, Budzowska M, Davies SL, van Drunen E, Onizawa H, Beverloo HB, Maas A, Essers J, Hickson ID, Kanaar R.

Nat Struct Mol Biol. 2007 Nov;14(11):1096-104
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Publication Alert

Identification of Mutations That Decrease the Stability of a Fragment of Saccharomyces cerevisiae Chromosome III Lacking Efficient Replicators

James F. Theis, Ann Dershowitz, Carmela Irene, Clelia Maciariello, Michael L. Tobin, Giordano Liberi, Sahba Tabrizifard, Malgorzata Korus, Lucia Fabiani and Carol S. Newlon

Genetics, Vol. 177, 1445-1458
doi:10.1534/genetics.107.074690
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Publication Alert

Tetrahymena ORC contains a ribosomal RNA fragment that participates in rDNA origin recognition

Mohammad M Mohammad, Taraka R Donti, J Sebastian Yakisich, Aaron G Smith and Geoffrey M Kapler

EMBO Journal (2007) 26, 5048–5060, doi:10.1038/sj.emboj.7601919
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Post doctoral opportunities

Cell cycle and DNA damage regulation of the Cdt1 replication licensing factor
Function of Cut8 in DNA repair

Two post-doctoral positions, funded by Cancer Research UK, are available in these two areas. For further details of projects see tinyurl.com/26ye48; also Ralph et al. 7:1134, Kearsey et al. Mol Cell Biol 27:1558. Informal enquiries to stephen.kearsey@zoo.ox.ac.uk (Dept Zoology, University of Oxford).
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