Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain- terminating nucleosides Kaori Kobayashi, Thomas A. Guilliam, Masataka Tsuda, Junpei Yamamoto, Laura J. Bailey, Shigenori Iwai, Shunichi Takeda, Aidan J. Doherty & Kouji Hirota Cell Cycle 15 1997-2008
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DNA replication origins—where do we begin? Marie-Noëlle Prioleau1 and David M. MacAlpine Genes Dev. August 1, 2016 30: 1683-1697
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A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation SimonGemble,GéraldineBuhagiar-Labarched̀e,RosineOnclercq-Delic,DenisBiard, Sarah Lambert and Mounira Amor-Guéret J. Cell Science 129 3167
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ORChestrating the human DNA replication program David M. MacAlpine PNAS 113 9136 - 9138
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Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers Benoit Miottoa, Zhe Jia, and Kevin Struhl PNAS 113 e4819
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RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells Vaclav Urban, Jana Dobrovolna, Daniela Hühn, Jana Fryzelkova, Jiri Bartek and Pavel Janscak JCB vol. 214 no. 4 401-415
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Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome Catarina P. Samora, Julie Saksouk, Panchali Goswami, Ben O. Wade, Martin R. Singleton, Paul A. Bates, Armelle Lengronne, Alessandro Costa, Frank Uhlmann Mol cell Volume 63, Issue 3, p371–384, 4 August 2016
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Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase Fabrizio Villa, Aline C. Simon, Maria Angeles Ortiz Bazan, Mairi L. Kilkenny, David Wirthensohn, Mel Wightman, Dijana Matak-Vinkovíc, Luca Pellegrini, Karim Labib Volume 63, Issue 3, p385–396, 4 August 2016
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POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies Emmanuelle Nicolas, Erica A. Golemis, Sanjeevani Arora GeneVolume 590, Issue 1, 15 September 2016, Pages 128–141
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miR-30a can inhibit DNA replication by targeting RPA1 thus slowing cancer cell proliferation Zhenyou Zou, Mengjie Ni, Jing Zhang, Yongfeng Chen, Hongyu Ma, Shihan Qian, Longhua Tang, Jiamei Tang, Hailun Yao, Chengbin Zhao, Xiongwen Lu, Hongyang Sun, Jue Qian, Xiaoting Mao, Xulin Lu, Qun Liu, Juping Zen, Hanbing Wu, Zhaosheng Bao, Shudan Lin, Hongyu Sheng, Yunlong Li, Yong Liang, Zhiqiang Chen, Dan Zong Biochemical Journal 473(14) 2131-2139;
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Exceeding the limits – Cdc45 overexpression turns bad Christian Speck Cell cycle 15 Page 1809-1810
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Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides Kaori Kobayashi, Thomas A. Guilliam, Masataka Tsuda, Junpei Yamamoto, Laura J. Bailey, Shigenori Iwai, Shunichi Takeda, Aidan J. Doherty & Kouji Hirota Cell Cycle 15 Page 1997-2008
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A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp Amanda S. Altieri, Jane E. Ladner, Zhuo Li, Howard Robinson, Zahur F.Sallman, John P. Marino, and Zvi Kelman Nucl. Acids Res. 2016 44: 6232-6241
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The Replication of Frataxin Gene Is Assured by Activation of Dormant Origins in the Presence of a GAA-Repeat Expansion Martina Stevanoni , Elisa Palumbo , Antonella Russo PLoS Genet 12(7): e1006201.
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