Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Myc and the Replicative CMG Helicase: The Creation and Destruction of Cancer Damon R. Reed Mark G. Alexandrow Bioessays Volume42, Issue4
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Opportunities for new studies of nuclear DNA replication enzymology in budding yeast Marta A. Garbacz, Scott A. Lujan & Thomas A. Kunkel Current Genetics volume 66, pages299–302(2020)
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SSRP1-mediated histone H1 eviction promotes replication origin assembly and accelerated development Lucia Falbo, Erica Raspelli, Francesco Romeo, Simona Fiorani, Federica Pezzimenti, Francesca Casagrande, Ilaria Costa, Dario Parazzoli & Vincenzo Costanzo NATURE COMMUNICATIONS | (2020)11:1345
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FAM111A protects replication forks from protein obstacles via its trypsin-like domain Yusuke Kojima, Yuka Machida, Sowmiya Palani, Thomas R. Caulfield, Evette S. Radisky, Scott H. Kaufmann & Yuichi J. Machida NATURE COMMUNICATIONS | (2020)11:1318
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DNA polymerase δ proofreads errors made by DNA polymerase ε Chelsea R. Bulock, Xuanxuan Xing, and Polina V. Shcherbakova PNAS March 17, 2020 117 (11) 6035-6041
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Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO–POL enzyme Shreya Ghosh, Yehuda Goldgur, Stewart Shuman Nucleic Acids Research, Volume 48, Issue 6, 06 April 2020, Pages 3165–3180,
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Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles Anupam Singh, Manjula Pandey, Divya Nandakumar, Kevin D Raney, Y Whitney Yin, Smita S Patel EMBO J (2020)39:e103367
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Structure of the processive human Pol δ holoenzyme Claudia Lancey, Muhammad Tehseen, Vlad-Stefan Raducanu, Fahad Rashid, Nekane Merino, Timothy J. Ragan, Christos G. Savva, Manal S. Zaher, Afnan Shirbini, Francisco J. Blanco, Samir M. Hamdan & Alfredo De Biasio Nature Communications volume 11, Article number: 1109 (2020)
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PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells Annabel Quinet, Stephanie Tirman, Jessica Jackson, Saša Šviković, Delphine Lemaçon, Denisse Carvajal-Maldonado, Daniel González-Acosta, Alexandre T. Vessoni, Emily Cybulla, Matthew Wood, Steven Tavis, Luis F.Z. Batista, Juan Méndez, Julian E. Sale, Alessandro Vindigni Mol Cell VOLUME 77, ISSUE 3, P461-474.E9,
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Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer Hu Fang, Jayne A. Barbour, Rebecca C. Poulos, Riku Katainen, Lauri A. Aaltonen, Jason W. H. Wong PLoS Genet 16(2): e1008572
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Inactivating Mutations in Exonuclease and Polymerase Domains in DNA Polymerase Delta Alter Sensitivities to Inhibitors of dNTP Synthesis Jiaming Zhang, Deyin Hou, James Annis, Forough Sargolzaeiaval, Julia Appelbaum, Eishi Takahashi, George M. Martin, Alan Herr, and Junko Oshima DNA and Cell BiologyVol. 39, No. 1
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DNA unwinding mechanism of a eukaryotic replicative CMG helicase Zuanning Yuan, Roxana Georgescu, Lin Bai, Dan Zhang, Huilin Li & Michael E. O’Donnell Nature Communications volume 11, Article number: 688 (2020)
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HBO1 (KAT7) Does Not Have an Essential Role in Cell Proliferation, DNA Replication, or Histone 4 Acetylation in Human Cells Andrew J. Kueh, Samantha Eccles, Leonie Tang, Alexandra L. Garnham, Rose E. May, Marco J. Herold, Gordon K. Smyth, Anne K. Voss, Tim Thomas Mol Cell Biol 40:e00506-19.
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