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31-Mar-2020 11:07
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Myc and the Replicative CMG Helicase: The Creation and Destruction of Cancer
Damon R. Reed Mark G. Alexandrow
Bioessays Volume42, Issue4
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31-Mar-2020 11:02
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Opportunities for new studies of nuclear DNA replication enzymology in budding yeast
Marta A. Garbacz, Scott A. Lujan & Thomas A. Kunkel
Current Genetics volume 66, pages299–302(2020)
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31-Mar-2020 11:00
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SSRP1-mediated histone H1 eviction promotes replication origin assembly and accelerated development
Lucia Falbo, Erica Raspelli, Francesco Romeo, Simona Fiorani, Federica Pezzimenti, Francesca Casagrande, Ilaria Costa, Dario Parazzoli & Vincenzo Costanzo
NATURE COMMUNICATIONS | (2020)11:1345
publication alert
31-Mar-2020 10:59
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FAM111A protects replication forks from protein obstacles via its trypsin-like domain
Yusuke Kojima, Yuka Machida, Sowmiya Palani, Thomas R. Caulfield, Evette S. Radisky, Scott H. Kaufmann & Yuichi J. Machida
NATURE COMMUNICATIONS | (2020)11:1318
publication alert
31-Mar-2020 10:56
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DNA polymerase δ proofreads errors made by DNA polymerase ε
Chelsea R. Bulock, Xuanxuan Xing, and Polina V. Shcherbakova
PNAS March 17, 2020 117 (11) 6035-6041
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31-Mar-2020 10:54
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Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO–POL enzyme
Shreya Ghosh, Yehuda Goldgur, Stewart Shuman
Nucleic Acids Research, Volume 48, Issue 6, 06 April 2020, Pages 3165–3180,
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16-Mar-2020 09:29
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Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles
Anupam Singh, Manjula Pandey, Divya Nandakumar, Kevin D Raney, Y Whitney Yin, Smita S Patel
EMBO J (2020)39:e103367
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16-Mar-2020 09:29
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Structure of the processive human Pol δ holoenzyme
Claudia Lancey, Muhammad Tehseen, Vlad-Stefan Raducanu, Fahad Rashid, Nekane Merino, Timothy J. Ragan, Christos G. Savva, Manal S. Zaher, Afnan Shirbini, Francisco J. Blanco, Samir M. Hamdan & Alfredo De Biasio
Nature Communications volume 11, Article number: 1109 (2020)
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16-Mar-2020 09:28
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PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
Annabel Quinet, Stephanie Tirman, Jessica Jackson, Saša Šviković, Delphine Lemaçon, Denisse Carvajal-Maldonado, Daniel González-Acosta, Alexandre T. Vessoni, Emily Cybulla, Matthew Wood, Steven Tavis, Luis F.Z. Batista, Juan Méndez, Julian E. Sale, Alessandro Vindigni
Mol Cell VOLUME 77, ISSUE 3, P461-474.E9,
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16-Mar-2020 09:26
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Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer
Hu Fang, Jayne A. Barbour, Rebecca C. Poulos, Riku Katainen, Lauri A. Aaltonen, Jason W. H. Wong
PLoS Genet 16(2): e1008572
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16-Mar-2020 09:24
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Inactivating Mutations in Exonuclease and Polymerase Domains in DNA Polymerase Delta Alter Sensitivities to Inhibitors of dNTP Synthesis
Jiaming Zhang, Deyin Hou, James Annis, Forough Sargolzaeiaval, Julia Appelbaum, Eishi Takahashi, George M. Martin, Alan Herr, and Junko Oshima
DNA and Cell BiologyVol. 39, No. 1
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16-Mar-2020 09:22
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DNA unwinding mechanism of a eukaryotic replicative CMG helicase
Zuanning Yuan, Roxana Georgescu, Lin Bai, Dan Zhang, Huilin Li & Michael E. O’Donnell
Nature Communications volume 11, Article number: 688 (2020)
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16-Mar-2020 09:20
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HBO1 (KAT7) Does Not Have an Essential Role in Cell Proliferation, DNA Replication, or Histone 4 Acetylation in Human Cells
Andrew J. Kueh, Samantha Eccles, Leonie Tang, Alexandra L. Garnham, Rose E. May, Marco J. Herold, Gordon K. Smyth, Anne K. Voss, Tim Thomas
Mol Cell Biol 40:e00506-19.