Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

publication alert

25-Sep-2017 13:59 | Permalink
Crystal structure of the human Polϵ B-subunit in complex with the C-terminal domain of the catalytic subunit Andrey G. Baranovskiy, Jianyou Gu, Nigar D. Babayeva, Igor Kurinov, Youri I. Pavlov and Tahir H. Tahirov J. Biol. Chem. 2017; 292:15717-15730
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publication alert

25-Sep-2017 13:59 | Permalink
Linchpin DNA-binding residues serve as go/no-go controls in the replication factor C-catalyzed clamp-loading mechanism Juan Liu, Yayan Zhou and Manju M. Hingorani J. Biol. Chem. 2017; 292:15892-15906
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publication alert

25-Sep-2017 13:58 | Permalink
Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro Dekang Liu; Jane H. Frederiksen; Sascha E. Liberti; Anne Lützen; Guido Keijzers... Nucleic Acids Research, Volume 45, Issue 16, 19 September 2017, Pages 9427–9440
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publication alert

25-Sep-2017 13:58 | Permalink
STN1–POLA2 interaction provides a basis for primase-pol α stimulation by human STN1 Swapna Ganduri Neal F. Lue Nucleic Acids Research, Volume 45, Issue 16, 19 September 2017, Pages 9455–9466,
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publication alert

18-Sep-2017 09:15 | Permalink
Human ribonuclease H1 resolves R-loops and thereby enables progression of the DNA replication fork Shankar Parajuli, Daniel C. Teasley, Bhavna Murali, Jessica Jackson, Alessandro Vindigni and Sheila A. Stewart J. Biol. Chem. 2017; 292:15216-15224
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publication alert

18-Sep-2017 09:14 | Permalink
Histone H4K20 tri‐methylation at late‐firing origins ensures timely heterochromatin replication Julien Brustel, Nina Kirstein, Fanny Izard, Charlotte Grimaud, Paulina Prorok, Christelle Cayrou, Gunnar Schotta, Alhassan F Abdelsamie, Jérôme Déjardin, Marcel Méchali, Giuseppe Baldacci, Claude Sardet, Jean‐Charles Cadoret, Aloys SchepersEric Julien The EMBO Journal (2017) 36: 2726–2741
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publication alert

08-Sep-2017 13:33 | Permalink
Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymerase Rubén Agudo Patricia A. Calvo María I. Martínez-Jiménez Luis Blanco Nucleic Acids Research, Volume 45, Issue 15, 6 September 2017, Pages 9046–9058,
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publication alert

08-Sep-2017 13:31 | Permalink
Mutant analysis of Cdt1's function in suppressing nascent strand elongation during DNA replication in Xenopus egg extracts Yuta Nakazaki, Takashi Tsuyama,Yutaro Azuma, Mikiko Takahashi, Shusuke Tada BBRC Volume 490, Issue 4, 2 September 2017, Pages 1375-1380
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publication alert

08-Sep-2017 13:29 | Permalink
Identification and characterization of ARS-like sequences as putative origin(s) of replication in human malaria parasite Plasmodium falciparum Meetu Agarwal,Krishanu Bhowmick,Kushal Shah,Annangarachari Krishnamachari,Suman Kumar Dhar Febs J. Volume 284, Issue 16 August 2017 Pages 2674–2695
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publication alert

08-Sep-2017 13:27 | Permalink
Retrotransposons are specified as DNA replication origins in the gene-poor regions of Arabidopsis heterochromatin Zaida Vergara Joana Sequeira-Mendes Jordi Morata Ramón Peiró Elizabeth Hénaff Celina Costas Josep M. Casacuberta Crisanto Gutierrez Nucleic Acids Research, Volume 45, Issue 14, 21 August 2017, Pages 8358–8368,
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