Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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The Replication Initiation Protein Sld2 Regulates Helicase Assembly Irina Bruck and Daniel L. Kaplan J. Biol. Chem. 2014 289: 1948-1959
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DNA replication and spindle checkpoints cooperate during S phase to delay mitosis and preserve genome integrity Maria M. Magiera, Elisabeth Gueydon, and Etienne Schwob JCB 204:165-175
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The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing Rebecca A. Frum, Shilpa Singh, Catherine Vaughan, Nitai D. Mukhopadhyay, Steven R. Grossman, Brad Windle, Sumitra Deb and Swati Palit Deb Nucl. Acids Res. (2014) 42 (2): 926-940
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The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression Marietta YWT Lee, Sufang Zhang, Szu Hua Sharon Lin, Xiaoxiao Wang, Zbigniew Darzynkiewicz, Zhongtao Zhang and Ernest YC Lee Cell cycle 13 Pages 23 – 31
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Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ Matthew Hogg, Pia Osterman, Göran O Bylund, Rais A Ganai, Else-Britt Lundström, A Elisabeth Sauer-Eriksson & Erik Johansson Nature Structural & Molecular Biology 21, 49–55 (2014)
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Prereplication-complex formation: a molecular double take? Hasan Yardimci & Johannes C Walter Nature Structural & Molecular Biology 21, 20–25 (2014
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Look Ma, no PCNA: how DNA polymerase ε synthesizes long stretches of DNA without a processivity factor Karl E Zahn & Sylvie Doublié Nature Structural & Molecular Biology 21, 12–14 (2014)
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Causes and consequences of replication stress Michelle K. Zeman & Karlene A. Cimprich Nature Cell Biology 16, 2–9 (2014)
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New histone supply regulates replication fork speed and PCNA unloading Jakob Mejlvang, Yunpeng Feng, Constance Alabert, Kai J. Neelsen, Zuzana Jasencakova, Xiaobei Zhao, Michael Lees, Albin Sandelin, Philippe Pasero, Massimo Lopes, and Anja Groth JCB vol. 204 no. 1 29-43
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An Iron–Sulfur Cluster in the Polymerase Domain of Yeast DNA Polymerase ε Rinku Jain, Eva S. Vanamee, Boris G. Dzikovski, Angeliki Buku, Robert E. Johnson, Louise Prakash, Satya Prakash, Aneel K. Aggarwal Journal of Molecular Biology Volume 426, Issue 2, 23 January 2014, Pages 301–308
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Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase Sivaraja Vaithiyalingam, Diana R. Arnett, Amit Aggarwal1, Brandt F. Eichman, Ellen Fanning, Walter J. Chazin Journal of Molecular Biology Volume 426, Issue 3, 6 February 2014, Pages 558–569
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