Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

19-Apr-2012 19:49 | Permalink
Regulation and spatial organization of PCNA in Trypanosoma brucei

Doris Kaufmanna, Alwine Gassena, Andreas Maiser, Heinrich Leonhardt, Christian J. Janzen

Biochemical and Biophysical Research Communications Volume 419, Issue 4, Pages 698–702
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Publication Alert

19-Apr-2012 19:49 | Permalink
Histone H3 Lysine 56 Methylation Regulates DNA Replication through Its Interaction with PCNA

Yongxin Yu, Chunying Song, Qiongyi Zhang, Peter A. DiMaggio, Benjamin A. Garcia, Autumn York, Michael F. Carey, Michael Grunstein

Molecular Cell, Volume 46, Issue 1, 7-17, 13 April 2012
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Publication Alert

19-Apr-2012 19:48 | Permalink
Altered Replication in Human Cells Promotes DMPK (CTG)n · (CAG)n Repeat Instability

Guoqi Liu, Xiaomi Chen, Yanzhe Gao, Todd Lewis, Joanna Barthelemy, and Michael Leffak

Mol. Cell. Biol. May 2012 32:1618-1632
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19-Apr-2012 19:47 | Permalink
DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1

Anna Travesa, Dwight Kuo, Robertus A M de Bruin, Tatyana I Kalashnikova, Marisela Guaderrama, Kevin Thai, Aaron Aslanian, Marcus B Smolka, John R Yates III, Trey Ideker and Curt Wittenberg

The EMBO Journal (2012), 31,1811 – 1822
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19-Apr-2012 19:46 | Permalink
Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes

Francisco M Bastos de Oliveira, Michael R Harris, Pijus Brazauskas, Robertus A M de Bruin and Marcus B Smolka

The EMBO Journal (2012), 31,1798 – 1810
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19-Apr-2012 19:45 | Permalink
RPA facilitates telomerase activity at chromosome ends in budding and fission yeasts

Pierre Luciano, Stéphane Coulon, Virginie Faure, Yves Corda, Julia Bos, Steven J Brill, Eric Gilson, Marie-Noelle Simon and Vincent Géli

The EMBO Journal (2012) 31, 2034 - 2046
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19-Apr-2012 19:44 | Permalink
Structural insights into the Cdt1-mediated MCM2–7 chromatin loading

Changdong Liu, Rentian Wu, Bo Zhou, Jiafeng Wang, Zhun Wei, Bik K. Tye, Chun Liang, and Guang Zhu

Nucl. Acids Res. (2012) 40(7): 3208-3217
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19-Apr-2012 19:43 | Permalink
Human telomeres replicate using chromosome-specific, rather than universal, replication programs

William C. Drosopoulos, Settapong T. Kosiyatrakul, Zi Yan, Simone G. Calderano, and Carl L. Schildkraut

JCB vol. 197 no. 2 253-266
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19-Apr-2012 19:43 | Permalink
The Werner Syndrome Exonuclease Facilitates DNA Degradation and High Fidelity DNA Polymerization by Human DNA Polymerase δ

Ashwini S. Kamath-Loeb, Jiang-Cheng Shen, Michael W. Schmitt, and Lawrence A. Loeb

J. Biol. Chem. 2012 287: 12480-12490
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19-Apr-2012 19:42 | Permalink
ATM Protein Physically and Functionally Interacts with Proliferating Cell Nuclear Antigen to Regulate DNA Synthesis

Armin M. Gamper, Serah Choi, Yoshihiro Matsumoto, Dibyendu Banerjee, Alan E. Tomkinson and Christopher J. Bakkenist

The Journal of Biological Chemistry, 287, 12445-12454.
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19-Apr-2012 19:41 | Permalink
Phosphorylation of ORC2 Protein Dissociates Origin Recognition Complex from Chromatin and Replication Origins

Kyung Yong Lee, Sung Woong Bang, Sang Wook Yoon, Seung-Hoon Lee, Jong-Bok Yoon and Deog Su Hwang

The Journal of Biological Chemistry, 287, 11891-11898
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19-Apr-2012 19:40 | Permalink
Regulation of cell cycle progression by forkhead transcription factor FOXO3 through its binding partner DNA replication factor Cdt1

Yiru Zhang, Yuqian Xing, Lei Zhang, Yang Mei, Kazuo Yamamoto, Tak W. Mak, and Han You,

PNAS April 10, 2012 vol. 109 no. 15 5717-5722
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19-Apr-2012 19:39 | Permalink
Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase ε in rolling circle DNA synthesis

Young-Hoon Kang, Wiebke Chemnitz Galal, Andrea Farina, Inger Tappin, and Jerard Hurwitz

PNAS 2012 109 (16) 6042-6047
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19-Apr-2012 19:39 | Permalink
The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

Alex J. Kuo, Jikui Song, Peggie Cheung, Satoko Ishibe-Murakami, Sayumi Yamazoe, James K. Chen, Dinshaw J. Patel & Or Gozani

Nature 484, 115–119
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19-Apr-2012 19:37 | Permalink
Evaluation of MCM-2 Expression in TMA Cervical Specimens

Alcina F. Nicol1, José R. Lapa e Silva, Cynthia B. Cunha, Sergio M. Amaro-Filho, Nathalia Oliveira, Beatriz Grinsztejn, Ruth Khalil, Fabio Russomano, Andrea Pires, Jonathan E. Golub, Gerard J. Nuovo

PLoS ONE 7(4): e32936
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03-Apr-2012 16:44 | Permalink
Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells

Hiroshi Arakawa, Theresa Bednar, Minli Wang, Katja Paul, Emil Mladenov, Alena A. Bencsik-Theilen and George Iliakis

Nucl. Acids Res. (2012) 40 (6): 2599-2610
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03-Apr-2012 16:43 | Permalink
Cdt1 Is Differentially Targeted for Degradation by Anticancer Chemotherapeutic Drugs

Athanasia Stathopoulou, Vassilis Roukos, Chariklia Petropoulou, Panagiotis Kotsantis, Nickolas Karantzelis, Hideo Nishitani, Zoi Lygerou2, Stavros Taraviras

PLoS ONE 7(3): e34621
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03-Apr-2012 16:42 | Permalink
Direct Role for Proliferating Cell Nuclear Antigen in Substrate Recognition by the E3 Ubiquitin Ligase CRL4Cdt2

Courtney G. Havens, Nadia Shobnam, Estrella Guarino, Richard C. Centore, Lee Zou, Stephen E. Kearsey and Johannes C. Walter

Journal of Biological Chemistry, 287,
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03-Apr-2012 16:41 | Permalink
Embryonic onset of late replication requires Cdc25 down-regulation

Jeffrey A. Farrell, Antony W. Shermoen, Kai Yuan, and Patrick H. O'Farrell

Genes Dev. April 1, 2012 26: 714-725
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Publication Alert

03-Apr-2012 16:40 | Permalink
Preventing Replication Stress to Maintain Genome Stability: Resolving Conflicts between Replication and Transcription

Rodrigo Bermejo, Mong Sing Lai, Marco Foiani

Molecular Cell, Volume 45, Issue 6, 710-718
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