Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

Mutation at the Polymerase Active Site of Mouse DNA Polymerase Increases Genomic Instability and Accelerates Tumorigenesis

Ranga N. Venkatesan, Piper M. Treuting, Evan D. Fuller, Robert E. Goldsby, Thomas H. Norwood, Ted A. Gooley, Warren C. Ladiges, Bradley D. Preston, and Lawrence A. Loeb

Molecular and Cellular Biology, November 2007, p. 7669-7682, Vol. 27, No. 21
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Publication Alert

Structural Changes in Mcm5 Protein Bypass Cdc7-Dbf4 Function and Reduce Replication Origin Efficiency in Saccharomyces cerevisiae

Margaret L. Hoang, Ronald P. Leon, Luis Pessoa-Brandao, Sonia Hunt,, M. K. Raghuraman, Walton L. Fangman, Bonita J. Brewer, and Robert A. Sclafani

Molecular and Cellular Biology, November 2007, p. 7594-7602, Vol. 27, No. 21
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Publication Alert

Suppression of gross chromosomal rearrangements by a new alternative replication factor C complex

Soma Banerjeea, Nilabja Sikdara and Kyungjae Myung

Biochemical and Biophysical Research Communications 362, 546-549
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Publication Alert

Cdc45 degradation during differentiation and apoptosis

S. Pollok and F. Grosse

Biochemical and Biophysical Research Communications 362 910-915
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Publication Alert

Three eukaryote-like Orc1/Cdc6 proteins functionally interact and mutually regulate their activities of binding to the replication origin in the hyperthermophilic archaeon Sulfolobus solfataricus P2

Jun Wang, Pei-Xia Jiang, Hui Feng, Ying Feng and Zheng-Guo He

Bioc.biop.res.comm 363 (1) 63-70
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Publication Alert

Hexameric ring structure of human MCM10 DNA replication factor

Andrei L Okorokov, Alastair Waugh, Julie Hodgkinson, Andal Murthy, Hye Kyung Hong, Elisabetta Leo, Michael B Sherman, Kai Stoeber, Elena V Orlova & Gareth H Williams

EMBO reports 8, 10, 925–930 (2007)
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Publication Alert

Identification and Characterization of Human Cdc7 Nuclear Retention and Export Sequences in the Context of Chromatin Binding

Byung Ju Kim, So-Young Kim, and Hoyun Lee

J. Biol. Chem., Vol. 282, Issue 41, 30029-30038, October 12, 2007
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Publication Alert

Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification

Valerie Notenboom, Richard G. Hibbert, Sarah E. van Rossum-Fikkert, Jesper V. Olsen, Matthias Mann and Titia K. Sixma*


Nucleic Acids Research, 2007, Vol. 35, No. 17 5819-5830
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Publication Alert

Properties of an unusual DNA primase from an archaeal plasmid

Kirsten Beck and Georg Lipps*

Nucleic Acids Research, 2007, Vol. 35, No. 17 5635-5645
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Publication Alert

Low rate of replication fork progression lengthens the replication timing of a locus containing an early firing origin

Marianne Bénard*, Chrystelle Maric and Gérard Pierron

Nucleic Acids Research, 2007, Vol. 35, No. 17 5763-5774
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Publication Alert

Low rate of replication fork progression lengthens the replication timing of a locus containing an early firing origin

Marianne Bénard*, Chrystelle Maric and Gérard Pierron

Nucleic Acids Research, 2007, Vol. 35, No. 17 5763-5774
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Publication Alert

Human Mcm10 Regulates the Catalytic Subunit of DNA Polymerase- and Prevents DNA Damage during Replication

Sharbani Chattopadhyay, and Anja-Katrin Bielinsky

Vol. 18, Issue 10, 4085-4095, October 2007
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Publication Alert

Mrc1 and Tof1 Regulate DNA Replication Forks in Different Ways during Normal S Phase

Ben Hodgson*,, Arturo Calzada,, and Karim Labib

Vol. 18, Issue 10, 3894-3902, October 2007
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