Implications of Translesion DNA Synthesis Polymerases on Genomic Stability and Human Health Jegadheeswari Venkadakrishnan, Ganesh Lahane, Arti Dhar, Wei Xiao, Krishna Moorthi Bhat, Tej K. PanditaORCID Icon & Audesh Bhat Mol Cell Biol 43 Pages 401-425

NFIB facilitates replication licensing by acting as a genome organizer Wenting Zhang, Yue Wang, Yongjie Liu, Cuifang Liu, Yizhou Wang, Lin He, Xiao Cheng, Yani Peng, Lu Xia, Xiaodi Wu, Jiajing Wu, Yu Zhang, Luyang Sun, Ping Chen, Guohong Li, Qiang Tu, Jing Liang & Yongfeng Shang Nature Communications volume 14, Article number: 5076 (2023)

How Pol α-primase is targeted to replisomes to prime eukaryotic DNA replication Morgan L. Jones, Valentina Aria, Yasemin Baris, Joseph T.P. Yeeles Mol Cell VOLUME 83, ISSUE 16, P2911-2924.E16

Dimeric G-quadruplex motifs-induced NFRs determine strong replication origins in vertebrates Jérémy Poulet-Benedetti, Caroline Tonnerre-Doncarli, Anne-Laure Valton, Marc Laurent, Marie Gérard, Natalja Barinova, Nikolaos Parisis, Florian Massip, Franck Picard & Marie-Noëlle Prioleau Nature Communications volume 14, Article number: 4843 (2023)

Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3 Frederick Richards, Marta J. Llorca-Cardenosa, Jamie Langton, Sara C. Buch-Larsen, Noor F. Shamkhi, Abhishek Bharadwaj Sharma, Michael L. Nielsen & Nicholas D. Lakin Nature Communications volume 14, Article number: 4310 (2023)

ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins Aina Maria Mas, Enrique Goñi, Igor Ruiz de los Mozos, Aida Arcas, Luisa Statello, Jovanna González, Lorea Blázquez, Wei Ting Chelsea Lee, Dipika Gupta, Álvaro Sejas, Shoko Hoshina, Alexandros Armaos, Gian Gaetano Tartaglia, Shou Waga, Jernej Ule, Eli Rothenberg, María Gómez & Maite Huarte Nature Communications volume 14, Article number: 4447 (2023)

CST–Polα/Primase: the second telomere maintenance machine Sarah W Cai and Titia de Lange Genes and Dev. 37:1–15

Changing protein–DNA interactions promote ORC binding-site exchange during replication origin licensing Annie Zhang, Larry J. Friedman, Jeff Gelles, and Stephen P. Bell PNAS 120 (30) e2305556120

Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing Audra L. Amasino, Shalini Gupta, Larry J. Friedman, Jeff Gelles, and Stephen P. Bell PNAS 120 (29) e2221484120

Firing of Replication Origins Is Disturbed by a CDK4/6 Inhibitor in a pRb-Independent Manner Su-Jung Kim, Chrystelle Maric, Lina-Marie Briu, Fabien Fauchereau, Giuseppe Baldacci, Michelle Debatisse, Stéphane Koundrioukoff, Jean-Charles Cadoret IJMS Volume 24 Issue 13 10.3390/ijms241310629

Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability Vincent Gaggioli, Calvin S. Y. Lo, Nazaret Reverón-Gómez, Zuzana Jasencakova, Heura Domenech, Hong Nguyen, Simone Sidoli, Andrey Tvardovskiy, Sidrit Uruci, Johan A. Slotman, Yi Chai, João G. S. C. Souto Gonçalves, Eleni Maria Manolika, Ole N. Jensen, David Wheeler, Sriram Sridharan, Sanjiban Chakrabarty, Jeroen Demmers, Roland Kanaar, Anja Groth & Nitika Taneja Nature Cell Biology volume 25, pages 1017–1032 (2023)

Transient chromatin compaction in fork restart Susan M. Gasser Nature Cell Biology volume 25, pages 931–932 (2023)

Interactions between Fkh1 monomers stabilize its binding to DNA replication origins Allan Reinapae, Ivar Ilves, Henel Jürgens, Signe Värv, Kersti Kristjuhan, Arnold Kristjuhan JBC VOLUME 299 105026, AUGUST 2023

Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe Jinal A Patel, Camryn Zezelic, Julie Rageul, Joanne Saldanha, Arafat Khan, Hyungjin Kim Nucleic Acids Research 51, Pages 6246–6263

Actin nucleators safeguard replication forks by limiting nascent strand degradation Jadwiga Nieminuszczy, Peter R Martin, Ronan Broderick, Joanna Krwawicz, Alexandra Kanellou, Camelia Mocanu, Vicky Bousgouni, Charlotte Smith, Kuo-Kuang Wen, Beth L Woodward, Chris Bakal, Fiona Shackley, Andrés Aguilera, Grant S Stewart, Yatin M Vyas, Wojciech Niedzwiedz Nucleic Acids Research, Volume 51, Pages 6337–6354,

Go along to get along: Integrator at active replication forks defuses co-directional transcription-replication conflicts Leticia Dinatto,Peter C. Stirling Mol Cell ISSUE 13, P2161-2163, JULY 06, 2023

Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability Rahul Bhowmick, Kavi P.M. Mehta, Mads Lerdrup, David Cortez Mol Cell 83,P2357-2366

A look into the dynamic process of proofreading in DNA polymerase-γ at near-atomic resolution Nature Structural & Molecular Biology volume 30, pages 722–723 (2023)

Polγ coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity Joon Park, Geoffrey K. Herrmann, Patrick G. Mitchell, Michael B. Sherman & Y. Whitney Yin Nature Structural & Molecular Biology volume 30, pages 812–823 (2023)

H4S47 O-GlcNAcylation regulates the activation of mammalian replication origins Yingying Zou, Jiayao Pei, Haizhen Long, Liting Lan, Kejian Dong, Tingting Wang, Ming Li, Zhexuan Zhao, Lirun Zhu, Gangxuan Zhang, Xin Jin, Yang Wang, Zengqi Wen, Min Wei & Yunpeng Feng Nature Structural & Molecular Biology volume 30, pages 800–811 (2023)

Distinct Interaction Modes for the Eukaryotic RNA Polymerase Alpha-like Subunits Alana E. Belkevich, Haleigh G. Pascual, Aula M. Fakhouri, David G. Ball & Bruce A. Knutson Mol Cell Biol 43 Pages 269-282

DNA polymerase ε leading strand signature mutations result from defects in its proofreading activity Robert E. Johnson, Louise Prakash, and Satya Prakash JBC 299 104293 June 2023,

Cell-type specificity of the human mutation landscape with respect to DNA replication dynamics Madison Caballero, Dominik Boos, Amnon Koren Mol Cell VOLUME 3, ISSUE 6, 100315

Structures of human primosome elongation complexes Qixiang He, Andrey G. Baranovskiy, Lucia M. Morstadt, Alisa E. Lisova, Nigar D. Babayeva, Benjamin L. Lusk, Ci Ji Lim & Tahir H. Tahirov Nature Structural & Molecular Biology volume 30, pages 579–583 (2023)

Human primase hangs on the primer–template and Polα to facilitate primer termination. He et al Nat Struct Mol Biol 30, 575–576 (2023).

CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands Clément Rouillon, Bruna V Eckhardt, Leonie Kollenstart, Fabian Gruss, Alexander E E Verkennis, Inge Rondeel, Peter H L Krijger, Giulia Ricci, Alva Biran, Theo van Laar, Charlotte M Delvaux de Fenffe, Georgiana Luppens, Pascal Albanese, Koichi Sato, Richard A Scheltema, Wouter de Laat, Puck Knipscheer, Nynke H Dekker, Anja Groth, Francesca Mattiroli Nucleic Acids Research, Volume 51, Pages 3770–3792

DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC Yejinpeng Wang, Lingao Ju, Gang Wang, Kaiyu Qian, Wan Jin, Mingxing Li, Jingtian Yu, Yiliang Shi, Yongzhi Wang, Yi Zhang, Yu Xiao & Xinghuan Wang Nature Communications volume 14, Article number: 2421 (2023)

Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk Mariève J. Rocque, Vilde Leipart, Ashish Kumar Singh, Pilar Mur, Maren F. Olsen, Lars F. Engebretsen, Edgar Martin-Ramos, Rosa Aligué, Pål Sætrom, Laura Valle, Finn Drabløs, Marit Otterlei & Wenche Sjursen MGG volume 298, pages 555–566 (2023)

RAD51 bypasses the CMG helicase to promote replication fork reversal WENPENG LIU, YUICHIRO SAITO, JESSICA JACKSON, RAHUL BHOWMICK, MASATO T. KANEMAKI, ALESSANDRO VINDIGNI, AND DAVID CORTEZ SCIENCE 380 pp. 382-387

Contributions of replicative and translesion DNA polymerases to mutagenic bypass of canonical and atypical UV photoproducts Brittany N. Vandenberg, Marian F. Laughery, Cameron Cordero, Dalton Plummer, Debra Mitchell, Jordan Kreyenhagen, Fatimah Albaqshi, Alexander J. Brown, Piotr A. Mieczkowski, John J. Wyrick & Steven A. Roberts Nature Communications volume 14, Article number: 2576 (2023)

DNA Damage-Induced, S-Phase Specific Phosphorylation of Orc6 is Critical for the Maintenance of Genome Stability Yo-Chuen Lin, Dazhen Liu, Arindam Chakraborty, Virgilia Macias, Eileen Brister, Jay Sonalkar, Linyuan Shen, Jaba Mitra, Taekjip Ha, Andre Kajdacsy-Balla, Kannanganattu V. Prasanth & Supriya G. Prasanth Mol Cell Biol 43 Pages 143-156